Intravenous prostaglandin F2alpha and amniotomy for the elective induction of labor at term.
نویسندگان
چکیده
In an earlier trial [7, 11] with intravenously administered PGF2# for the elective induction of multiparae at term, amniotomy was delayed to comply with FD A regulations. As a consequence, the Start of the electronic supervision was also postponed and thus the refined ässessment of the potential fetal ha2ards of PGF2& was prevented. The present study was tailored in accordance with the dual purpose of meeting our primary objective (to study the effects of PGF2# in the fetus and the newborn) by relying on a procedure actually used in clinical obstetrics, i. e. amniotomy followed by the intravenous infusion of an oxytocic drug.
منابع مشابه
Clinical trial comparing artificial rupture of membranes plus oral PGE2 tablets versus artificial rupture of membranes plus intravenous oxytocin for induction of labour in primigravid patients at term.
We report the results of a pilot study conducted to compare the efficacy of oral prostaglandin E2 versus intravenous oxytocin in inducing labour after lower amniotomy in 20 primigravid patients at term. The results suggest no significant differences in the performance of each group for the induction to delivery interval, the mode of delivery, the Apgar score at five minutes or for third stage a...
متن کاملInduction of labour by simultaneous intravenous administration of prostaglandin E 2 and oxytocin.
In a group of 20 matched primigravid patients labour was induced by forewater amniotomy followed by intravenous oxytocin (Syntocinon) administered in escalating doses. Ten of these patients, in a double-blind trial, also received prostaglandin E(2) infused simultaneously with the oxytocin. In the combined prostaglandin-oxytocin group there was a noticeable reduction in the dosage of oxytocin re...
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Labour was induced successfully at or near term in 34 out of 35 cases by combined amniotomy and intravenous infusion of either prostaglandins F(2)alpha, E(2), or E(1). Of particular importance is the finding of hypertonus in 4 of the 18 cases induced with prostaglandin E(2).
متن کاملProstaglandin E2 tablets compared with intravenous oxytocin in induction of labour.
Stimulation of uterine activity after amniotomy has been carried out with prostaglandin E2 (PGE2) tablets in two dosage regimens and with intravenous oxytocin. Oxytocin stimulation was the most successful. The difference in success rate was most marked in nulliparous patients and those with low Bishop score.
متن کاملRapid increases in plasma prostaglandin concentrations after vaginal examination and amniotomy.
Peripheral plasma concentrations of 13,14-dihydro-15-keto prostaglandin F (PGFM) were measured in three groups of women after the 37th week of pregnancy. Samples were taken before and five minutes after (a) amniotomy, (b) vaginal examination with sweeping of the fetal membranes, or (c) vaginal examination without sweeping of the membranes. Each procedure significantly raised the circulating PGF...
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ورودعنوان ژورنال:
- Journal of perinatal medicine
دوره 1 4 شماره
صفحات -
تاریخ انتشار 1973